Diethyl ethylmalonate → 2-Amino-2-ethyl-4-(4-octylphenyl)butanol

HRID 617600노트

반응식

HRID 617600 반응식
C([O:4][CH2:5][C:6]([NH:26]C(=O)C)([CH2:24][CH3:25])[CH2:7][CH2:8][C:9]1[CH:14]=[CH:13][C:12]([C:15](=O)[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])=[CH:11][CH:10]=1)(=O)C.C(OC(=O)C(CC)C(OCC)=O)C>>[NH2:26][C:6]([CH2:24][CH3:25])([CH2:7][CH2:8][C:9]1[CH:10]=[CH:11][C:12]([CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])=[CH:13][CH:14]=1)[CH2:5][OH:4]

참가 물질

3

반응물 2

HCID 8610Diethyl ethylmalonateHCID 53718772HCID 53718772, 화합물

생성물 1

HCID 226187412-Amino-2-ethyl-4-(4-octylphenyl)butanol

실험 절차

In working example 77, 2-acetamido-2-ethyl-4-(4-octanoylphenyl)butyl acetate obtained by using ethylmalonic acid diethyl ester instead of propylmalonic acid diethyl ester, is subjected to reduction in the same manner as working example 2 (7) and then hydrolysis in the same manner as working example 78 to give the subject compound.

후처리

  1. customobtained
  2. customhydrolysis in the same manner
  3. customto give the subject compound

출처 및 근거

ORD 기록
ord-987750befa8a4f81a0b4da325a5bdbb5
출처 데이터셋
uspto-grants-1999_09
특허 번호
US05948820

반응 노트

불러오는 중…