Diethyl ethylmalonate → 2-Amino-2-ethyl-4-[4-(1-hydroxyoctyl)phenyl]butanol

HRID 617601노트

반응식

HRID 617601 반응식
C([O:4][CH2:5][C:6]([NH:26]C(=O)C)([CH2:24][CH3:25])[CH2:7][CH2:8][C:9]1[CH:14]=[CH:13][C:12]([C:15](=[O:23])[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])=[CH:11][CH:10]=1)(=O)C.C(OC(=O)C(CC)C(OCC)=O)C>>[NH2:26][C:6]([CH2:24][CH3:25])([CH2:7][CH2:8][C:9]1[CH:10]=[CH:11][C:12]([CH:15]([OH:23])[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])=[CH:13][CH:14]=1)[CH2:5][OH:4]

참가 물질

3

반응물 2

HCID 8610Diethyl ethylmalonateHCID 53718772HCID 53718772, 화합물

생성물 1

HCID 226187962-Amino-2-ethyl-4-[4-(1-hydroxyoctyl)phenyl]butanol

실험 절차

In working example 77, 2-acetamido-2-ethyl-4-(4-octanoylphenyl)butyl acetate obtained by using ethylmalonic acid diethyl ester instead of propylmalonic acid diethyl ester, is treated in the same manners as working example 79 and then working example 80 to give the subject compound.

후처리

  1. customobtained
  2. additionis treated in the same manners
  3. customto give the subject compound

출처 및 근거

ORD 기록
ord-46539a9f00db4d518e5ff82697b519a2
출처 데이터셋
uspto-grants-1999_09
특허 번호
US05948820

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