2-Iodophenol → 4-(2-Iodophenoxymethyl)-1-methyl-1,2,3,6-tetrahydropyridine

반응식

[OH:1][CH2:2][C:3]1[CH2:4][CH2:5][N:6]([CH3:9])[CH2:7][CH:8]=1.[I:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1O>>[I:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[O:1][CH2:2][C:3]1[CH2:8][CH2:7][N:6]([CH3:9])[CH2:5][CH:4]=1

참가 물질

반응물 2

HCID 107842-Iodophenol

HCID 1189211,2,3,6-Tetrahydro-1-methylpyridine-4-methanol

생성물 1

HCID 107350934-(2-Iodophenoxymethyl)-1-methyl-1,2,3,6-tetrahydropyridine수율 74%

실험 절차

The title compound was prepared from 4-(hydroxymethyl)-1-methyl-1,2,3,6-tetrahydropyridine (D9) and 2-iodophenol, using a procedure similar to that of Description 1 in 74% yield.

출처 및 근거

ORD 기록: ord-99b56ac03cc64dc1ad0c748e9cfc6105
출처 데이터셋: uspto-grants-1999_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05952325

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