Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 6-Bromo-7-methoxy-1,1-dimethyl-3,4-dihydronaphthalen-2(1H)-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | N-bromobutanimide | HCID 67184 | — |
| 반응물 | 7-Methoxy-1,1-dimethyl-3,4-dihydronaphthalen-2(1H)-one | HCID 13011007 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | 6-Bromo-7-methoxy-1,1-dimethyl-3,4-dihydronaphthalen-2(1H)-one | HCID 54578543 | 92% |
반응 단계
7-Methoxy-1,1-dimethyl-3,4-dihydro-1H-naphthalen-2-one (Compound A2, 2.0 g, 9.791 mmol) was dissolved in CH3CN (40 mL), added with NBS (1.92 g, 1.1 eq.), and the mixture was stirred at room temperature for 2.5 hr. The reaction solution was added to water (40 mL), and the precipitated solid was filtered to obtain the title compound (white powder, 2.55 g, 92%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09440922B2 |
| 출처 데이터셋 | uspto-grants-2016_09 |
| ORD ID | ord-8e9ae7628b6f4ada9bc74a2a53f2b1c7 |
| 출처 메모 | uspto-grants-2016_09 |