2-Amino-2-(1,2-dihydroxy-4-octadecenyl)-1,3-propanediol → 2-Amino-2-(1,2-dihydroxyoctadecyl)-1,3-propanediol

HRID 617873노트

반응식

HRID 617873 반응식
[NH2:1][C:2]([CH:7]([OH:26])[CH:8]([OH:25])[CH2:9][CH:10]=[CH:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24])([CH2:5][OH:6])[CH2:3][OH:4]>CO.[C].[Pd]>[NH2:1][C:2]([CH:7]([OH:26])[CH:8]([OH:25])[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24])([CH2:3][OH:4])[CH2:5][OH:6]

참가 물질

4

반응물 1

HCID 538638012-Amino-2-(1,2-dihydroxy-4-octadecenyl)-1,3-propanediol

생성물 1

HCID 218493532-Amino-2-(1,2-dihydroxyoctadecyl)-1,3-propanediol수율 50.2%

시약·촉매·용매 2

HCID 178418390HCID 178418390, 화합물촉매HCID 887Methanol용매

실험 절차

2-Amino-2-(1,2-dihydroxy-4-octadecenyl)-1,3-propanediol (68.0 mg) was dissolved in 14 ml of methanol and 6.8 mg of 5% palladium-carbon was added thereto. The catalytic reduction was conducted at ordinary temperature and at atmospheric pressure day and night. After the reaction, the catalyst was filtered off and the filtrate was concentrated under reduced pressure to give 34.3 mg of the subject compound.

후처리

  1. customAfter the reaction
  2. filtrationthe catalyst was filtered off
  3. concentrationthe filtrate was concentrated under reduced pressure

출처 및 근거

ORD 기록
ord-dda39b44ffd84448bec54c3cc1259b31
출처 데이터셋
uspto-grants-1999_09
특허 번호
US05952316

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