Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Benzyloxycarbonylamino3-([1,8]naphthyridin-2-yl)-propane → 3-(5,6,7,8-Tetrahydro-1,8-naphthyridin-2-yl)propan-1-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Benzyloxycarbonylamino3-([1,8]naphthyridin-2-yl)-propane | HCID 21850009 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 촉매 | HCID 178418390 | HCID 178418390 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 3-(5,6,7,8-Tetrahydro-1,8-naphthyridin-2-yl)propan-1-amine | HCID 9877599 | — |
반응 단계
A mixture of 1-7 (0.40 g, 1.24 mmol) and 10% Pd/carbon (0.08 g) in EtOH (12 mL) was stirred under a balloon of hydrogen for 20 h. Filtration through a celite pad and then evaporative removal of the filtrate solvent gave 1-8 as a colorless oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05952341 |
| 출처 데이터셋 | uspto-grants-1999_09 |
| ORD ID | ord-b76cde09736546e88cde543518f2299b |
| 출처 메모 | uspto-grants-1999_09 |