N,N-Dimethyl-1,3-propanediamine → 6-(2,6-dichlorophenyl)-2-N-[3-(dimethylamino)propyl]pyrido[2,3-d]pyrimidine-2,7-diamine

HRID 617930

반응식

HRID 617930 반응식
[NH2:1][C:2]1[N:3]=[CH:4][C:5]2[CH:11]=[C:10]([C:12]3[C:17]([Cl:18])=[CH:16][CH:15]=[CH:14][C:13]=3[Cl:19])[C:9]([NH2:20])=[N:8][C:6]=2[N:7]=1.[CH3:21][N:22]([CH3:27])[CH2:23][CH2:24][CH2:25]N>>[NH2:20][C:9]1[C:10]([C:12]2[C:17]([Cl:18])=[CH:16][CH:15]=[CH:14][C:13]=2[Cl:19])=[CH:11][C:5]2[CH:4]=[N:3][C:2]([NH:1][CH2:25][CH2:24][CH2:23][N:22]([CH3:27])[CH3:21])=[N:7][C:6]=2[N:8]=1

참가 물질

3

반응물 2

HCID 7993N,N-Dimethyl-1,3-propanediamineHCID 53281136-(2,6-Dichlorophenyl)pyrido[2,3-d]pyrimidine-2,7-diamine

생성물 1

HCID 53281386-(2,6-dichlorophenyl)-2-N-[3-(dimethylamino)propyl]pyrido[2,3-d]pyrimidine-2,7-diamine

실험 절차

The title compound was prepared as in Example 20 by reacting 3.0 g of 2,7-diamino-6-(2,6-dichlorophenyl)-pyrido[2,3-d]pyrimidine from Example 1 and 60 mL of 3-(dimethylamino)propylamine to give the title compound.

후처리

  1. customThe title compound was prepared as in Example 20

출처 및 근거

ORD 기록
ord-c30f758495ca46278d4bc9de5f63e4e6
출처 데이터셋
uspto-grants-1999_09
특허 번호
US05952342

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