Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3',4',5'-Trimethoxyacetophenone → (E)-3-(6-Methoxyindol-3-yl)-1-(3,4,5-trimethoxyphenyl)-2-propen-1-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3',4',5'-Trimethoxyacetophenone | HCID 14345 | — |
| 반응물 | 6-Methoxy-1H-indole-3-carboxaldehyde | HCID 907214 | — |
| 생성물 | (E)-3-(6-Methoxyindol-3-yl)-1-(3,4,5-trimethoxyphenyl)-2-propen-1-one | HCID 21850283 | 32% |
반응 단계
Substantially the same procedure as in Example 1 was repeated using 3',4',5'-trimethoxyacetophenone (659 mg) and 6-methoxyindole-3-carboxaldehyde (550 mg) except that the reaction solution was concentrated under reduced pressure, that the residue was purified by silica gel column chromatography, and that the obtained crude crystals were recrystallized from ethanol, to give Compound 39 (369 mg).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05952355 |
| 출처 데이터셋 | uspto-grants-1999_09 |
| ORD ID | ord-f3c262c37ecd43e0955d3e99bad2ecf7 |
| 출처 메모 | uspto-grants-1999_09 |