Glycine ethyl ester → 3-(4-t-Butoxycarbonyl-1-piperazinyl)benzoyl glycine
반응식
[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][N:11]([C:14]2[CH:15]=[C:16]([CH:20]=[CH:21][CH:22]=2)[C:17](O)=[O:18])[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].C([O:25][C:26](=[O:29])[CH2:27][NH2:28])C>>[C:1]([O:5][C:6]([N:8]1[CH2:9][CH2:10][N:11]([C:14]2[CH:15]=[C:16]([CH:20]=[CH:21][CH:22]=2)[C:17]([NH:28][CH2:27][C:26]([OH:25])=[O:29])=[O:18])[CH2:12][CH2:13]1)=[O:7])([CH3:4])([CH3:2])[CH3:3]참가 물질
3
실험 절차
The acid 16-3 was coupled with glycine ethyl ester followed by hydrolysis of the resulting ester using previously described chemistry to yield 17-1.
후처리
- customto yield 17-1
출처 및 근거
- ORD 기록
- ord-9c0aa2c641d34997a350f62b2f44d9e3
- 출처 데이터셋
- uspto-grants-1999_09
- 특허 번호
- US05952306
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