Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 3-Chloro-8-hydroxy-2,6,6-trimethyl-5,6-dihydro-benzo[b]carbazol-11-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Einecs 211-027-4 | HCID 69401 | — |
| 반응물 | 3-Chloro-8-methoxy-2,6,6-trimethyl-5,6-dihydro-benzo[b]carbazol-11-one | HCID 66835015 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | 3-Chloro-8-hydroxy-2,6,6-trimethyl-5,6-dihydro-benzo[b]carbazol-11-one | HCID 66834489 | — |
반응 단계
3-Chloro-8-methoxy-2,6,6-trimethyl-5,6-dihydro-benzo[b]carbazol-11-one (Compound S1-2, 18.9 mg, 0.0556 mmol) and pyridinium chloride (220 mg, 34 eq.) were stirred at 185° C. for 2.5 hr. After cooling, the reaction solution was added with water and ethyl acetate, and the organic layer was washed with water and saturated brine, dried over magnesium sulfate, filtered and concentrated under reduced pressure to obtain the title compound as a crude product.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09440922B2 |
| 출처 데이터셋 | uspto-grants-2016_09 |
| ORD ID | ord-17e47f4a39f040848ac647653d11f511 |
| 출처 메모 | uspto-grants-2016_09 |