12-Methoxydodecanoate → 12-Methoxydodecanoyl chloride

HRID 618298노트

반응식

HRID 618298 반응식
[CH3:1][O:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][C:14](NCC1C=CC=CC=1)=[O:15].COCCCCCCCCCCCC(O)=O.C(Cl)(=O)C([Cl:43])=O>C1(C)C=CC=CC=1>[CH3:1][O:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][C:14]([Cl:43])=[O:15]

참가 물질

5

반응물 3

HCID 142012-MethoxydodecanoateHCID 65578Oxalyl chlorideHCID 979711912-Methoxy-N-(phenylmethyl)dodecanamide

생성물 1

HCID 1961175912-Methoxydodecanoyl chloride

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

Reaction Scheme 4 illustratively shows the preparation of 12-methoxy-N-(phenyl-methyl)dodecanamide wherein 12-methoxydodecanoic acid (8) is treated with oxalyl chloride in anhydrous toluene to form 12-methoxydodecanoyl chloride (9) which in turn reacts with benzylamine in methylene chloride to give the desired fatty acid amide (10).

후처리

  1. customReaction Scheme 4

출처 및 근거

ORD 기록
ord-7f44dd1b3e5e480b8de2afbed8beff66
출처 데이터셋
uspto-grants-1999_09
특허 번호
US05952377

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