Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Toluenesulfonyl chloride → 16-(p-Toluensulfonyloxy)hexadecanol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Toluenesulfonyl chloride | HCID 7397 | — |
| 반응물 | 1,16-Hexadecanediol | HCID 82184 | — |
| 용매 | Pyridine | HCID 1049 | — |
| 생성물 | 16-(p-Toluensulfonyloxy)hexadecanol | HCID 18366472 | 42% |
반응 단계
To a solution of 1.1 g of 1,16-dihydroxyhexadecane in 10 ml of dry pyridine 0.8 g of tosyl chloride was added. After 2 h mixture was concentrated diluted with 20 ml of acetone, 5 g of SiO2 was added and acetone was removed in vacuum. The solid was applied on SiO2 and eluted with pentane-ethyl acetate (2:1) to yield 748 mg (42%) of the compound of Structure 1 (C-101).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05955379 |
| 출처 데이터셋 | uspto-grants-1999_09 |
| ORD ID | ord-8b1394505c7540ba9c6bab1c0dc48fb1 |
| 출처 메모 | uspto-grants-1999_09 |