참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Imidazole | HCID 795 | — |
| 반응물 | 5-Chloro-2-nitrobenzonitrile | HCID 100506 | — |
| 용매 | Dimethylacetamide | HCID 31374 | — |
| 생성물 | 5-(1-Imidazolyl)-2-nitrobenzonitrile | HCID 21847820 | 107.8% |
반응 단계
A mixture of 5-chloro-2-nitrobenzonitrile (20.0 g) and imidazole (22.3 g) in DMA (150 ml) was heated at 140° C. for 6 hours. The mixture was evaporated and the residue was triturated with water to give 5-(1-imidazolyl)-2-nitrobenzonitrile (25.3 g); NMR Spectrum: (CD3SOCD3) 7.20 (d, 1H), 8.05 (t, 1H), 8.28 (m, 1H), 8.62 (m, 2H), 8.51 (d, 1H);
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05955464 |
|---|
| 출처 데이터셋 | uspto-grants-1999_09 |
|---|
| ORD ID | ord-d929b6519f5a4617a4c00bf24f28fa1a |
|---|
| 출처 메모 | uspto-grants-1999_09 |
|---|
