Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Salicylaldehyde → 2-(2-Morpholinoethoxy)benzaldehyde
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Salicylaldehyde | HCID 6998 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | Morpholine, 4-(2-chloroethyl)-, hydrochloride (1:1) | HCID 77210 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | 2-(2-Morpholinoethoxy)benzaldehyde | HCID 976593 | — |
반응 단계
To a solution of salicylaldehyde (2 ml) in acetonitrile (20 ml) was added K2CO3 (5.71 g), followed by N-(2-chloroethyl)morpholine hydrochloride (3.5 g) and then the mixture was stirred at room temperature for 2 hours, then at reflux overnight. The reaction mixture was cooled to room temperature, filtered, and the filtrate was concentrated in vacuo to afford 2-[2-(4-morpholinyl)ethoxy]benzaldehyde, as a yellow oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05958929 |
| 출처 데이터셋 | uspto-grants-1999_09 |
| ORD ID | ord-5ea47cfc774c4e04a4b58b4e7e74100b |
| 출처 메모 | uspto-grants-1999_09 |