HCID 57073292, 화합물 → HCID 57026923, 화합물
반응식
C(OC([NH:11][C@H:12]1[C@H:15]([O:16][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[NH:14][C:13]1=[O:23])=O)C1C=CC=CC=1.[H][H]>[Pd].C(OCC)(=O)C>[NH2:11][C@H:12]1[C@H:15]([O:16][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[NH:14][C:13]1=[O:23]참가 물질
5
실험 절차
(3S, 4S)-3-benzyloxycarbonylamino-4-phenoxy-azetidin-2-one (140 mg, 0.45 mmole) is hydrogenated with 100 mg of 10% palladium on activated carbon in ethyl acetate (20 ml) at 50 psi hydrogen pressure at room temperature for 2 hours. After removal of catalyst by filtration, deprotected (3S, 4S)-3-amino-4-phenoxy-azetidin-2-one in ethyl acetate is obtained.
후처리
- customAfter removal of catalyst
- filtrationby filtration
출처 및 근거
- ORD 기록
- ord-386b5e23b9844fdf97bb4b65651a0957
- 출처 데이터셋
- uspto-grants-1999_09
- 특허 번호
- US05959123
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