참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 4-Fluoro-3-nitroaniline | HCID 67768 | — |
| 반응물 | 5-Isoquinolinethiol | HCID 11051963 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 4-(5-Isoquinolylsulfanyl)-3-nitroaniline | HCID 21846909 | 96.5% |
반응 단계
5-Isoquinolinethiol 1.00 g (6.2 mmol) was dissolved in DMF 14 ml, potassium carbonate 1.01 g (7.3 mmol) and 4-fluoro-3-nitroaniline 0.96 g (6.1 mmol) were added and the mixture was heated with stirring for 2 hours at 100° C. The reaction solution was concentrated under reduced pressure, the resulting residue was washed with water to obtain 4-(5-isoquinolylsulfanyl)-3-nitroaniline 1.75 g (96.5%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05959107 |
|---|
| 출처 데이터셋 | uspto-grants-1999_09 |
|---|
| ORD ID | ord-318b0d5941c04fb2a4d3d90fcc4e93c2 |
|---|
| 출처 메모 | uspto-grants-1999_09 |
|---|
