7-methoxynaphthalene-2-sulfonic acid [1-(5-cyanothiophen-2-ylmethyl)-2-oxopyrrolidin-3-(S)-yl]amide → 7-Methoxynaphthalene-2-sulfonic acid [1-(5-cyanothiophen-2-ylmethyl)-2-oxopyrrolidin-3-(S)-Yl]-methylamide
반응식
[C:1]([C:3]1[S:7][C:6]([CH2:8][N:9]2[CH2:13][CH2:12][C@H:11]([NH:14][S:15]([C:18]3[CH:27]=[CH:26][C:25]4[C:20](=[CH:21][C:22]([O:28][CH3:29])=[CH:23][CH:24]=4)[CH:19]=3)(=[O:17])=[O:16])[C:10]2=[O:30])=[CH:5][CH:4]=1)#[N:2].[C:31](C1SC=C(CN2CC[C@H](NS(C3C=CC4C(=CC(OC)=CC=4)C=3)(=O)=O)C2=O)C=1)#N>>[C:1]([C:3]1[S:7][C:6]([CH2:8][N:9]2[CH2:13][CH2:12][C@H:11]([N:14]([CH3:31])[S:15]([C:18]3[CH:27]=[CH:26][C:25]4[C:20](=[CH:21][C:22]([O:28][CH3:29])=[CH:23][CH:24]=4)[CH:19]=3)(=[O:17])=[O:16])[C:10]2=[O:30])=[CH:5][CH:4]=1)#[N:2]참가 물질
3
실험 절차
The title compound is prepared as in EXAMPLE 126, Part A using 7-methoxynaphthalene-2-sulfonic acid [1-(5-cyanothiophen-2-ylmethyl)-2-oxopyrrolidin-3-(S)-yl]amide, prepared as in EXAMPLE 148, Part A, in place of 7-methoxynaphthalene-2-sulfonic acid [1-(5-cyanothiophen-3-ylmethyl)-2-oxopyrrolidin-3-(S)-yl]amide.
출처 및 근거
- ORD 기록