Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methacrylic Acid → 4-(N-2-hydroxyethyl-N-ethylamino)-4'-nitro-1,4-diphenyl-1,3-butadiene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methacrylic Acid | HCID 4093 | — |
| 반응물 | (4-Nitrophenyl)acetic acid | HCID 4661 | — |
| 반응물 | Aniline | HCID 6115 | — |
| 반응물 | 2-Methylbenzenesulfonic acid | HCID 6925 | — |
| 반응물 | 4-(N-2-hydroxyethyl-N-ethylamino)cinnamaldehyde | HCID 54451596 | — |
| 용매 | Water | HCID 962 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | 4-(N-2-hydroxyethyl-N-ethylamino)-4'-nitro-1,4-diphenyl-1,3-butadiene | HCID 54446572 | — |
반응 단계
A solution of 21.9 g (0.1 mole) of 4-(N-2-hydroxyethyl-N-ethylamino)cinnamaldehyde, 9.3 g (1 mole) of aniline, and 0.19 g (1 mole %) of toluenesulfonic acid in toluene is heated at reflux for 17 hours with azeotropic removal of water. After the mixture is cooled to room temperature, 17.2 g (0.2 mole) of methacrylic acid and 18.1 g (0.1 mole) of 4-nitrophenylacetic acid are added to the solution, and the reaction is stirred at room temperature for 3 hours. The mixture then is heated at reflux for 16 hours. After cooling to room temperature, the solid diphenylbutadiene precipitates from solution and is collected by filtration and purified by recrystallization from ethanol.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05247042 |
| 출처 데이터셋 | uspto-grants-1993_09 |
| ORD ID | ord-a7fdbb7f8cd94053be30d2daa540915e |
| 출처 메모 | uspto-grants-1993_09 |