참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 1-Butanol, 4-(butylamino)- | HCID 20669 | — |
| 반응물 | 4-Fluorobenzaldehyde | HCID 68023 | — |
| 용매 | Dimethyl Sulfoxide | HCID 679 | — |
| 생성물 | 4-(N-4-hydroxybutyl-N-butylamino)benzaldehyde | HCID 19795094 | — |
반응 단계
To a three neck flask fitted with a mechanical stirrer, a thermometer, and a condenser, is added 124 g (1 mole) of 4-fluorobenzaldehyde, 145.3 g (1 mole) of N-butyl-N-4-hydroxybutylamine, 138.2 g (1 mole) of anhydrous potassium carbonate, and dimethylsulfoxide. The mixture is then heated at 95° C. until the reaction is complete. After cooling to room temperature, the solution is poured into a four-fold excess of ice water, and the solid product is collected by filtration and purified by recrystallization from tetrahydrofuran/benzene.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05247042 |
|---|
| 출처 데이터셋 | uspto-grants-1993_09 |
|---|
| ORD ID | ord-4683026ba7114d0ab4a570be14f1d8a7 |
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| 출처 메모 | uspto-grants-1993_09 |
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