Methyl 4-[2-benzenesulphonamidoindan-5-yl]-4-oxobutyrate → HCID 14071508, 화합물

HRID 620196노트

반응식

HRID 620196 반응식
[C:1]1([S:7]([NH:10][CH:11]2[CH2:19][C:18]3[C:13](=[CH:14][CH:15]=[C:16]([C:20](=[O:27])[CH2:21][CH2:22][C:23]([O:25]C)=[O:24])[CH:17]=3)[CH2:12]2)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1>C(O)C>[C:1]1([S:7]([NH:10][CH:11]2[CH2:19][C:18]3[C:13](=[CH:14][CH:15]=[C:16]([C:20](=[O:27])[CH2:21][CH2:22][C:23]([OH:25])=[O:24])[CH:17]=3)[CH2:12]2)(=[O:9])=[O:8])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

참가 물질

3

반응물 1

HCID 14071507Methyl 4-[2-benzenesulphonamidoindan-5-yl]-4-oxobutyrate

생성물 1

HCID 14071508HCID 14071508, 화합물

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

2.7 ml of 15N sodium hydroxide solution are added to 8.3 g (21.4 mmol) of methyl 4-[2-benzenesulphonamidoindan-5-yl]-4-oxobutyrate in 20 ml of ethanol and the mixture is boiled for 2 hours. The mixture is evaporated in vacuo, the residue is taken up in water, and the reaction product is precipitated with hydrochloric acid. It is crystallised from ethyl acetate/diisopropyl ether.

후처리

  1. customThe mixture is evaporated in vacuo
  2. customthe reaction product is precipitated with hydrochloric acid
  3. customIt is crystallised from ethyl acetate/diisopropyl ether

출처 및 근거

ORD 기록
ord-4e477668029a4d19b09425406df9fe92
출처 데이터셋
uspto-grants-1989_04
특허 번호
US04820705

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