Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Carbonate → N-Hydroxyhexyl-1,2,3,4-tetrahydroquinoline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 1,2,3,4-Tetrahydroquinoline | HCID 69460 | — |
| 반응물 | 6-Bromo-1-hexanol | HCID 77970 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | N-Hydroxyhexyl-1,2,3,4-tetrahydroquinoline | HCID 19795093 | — |
반응 단계
A stirred solution of 133.2 g (1 mole) of 1,2,3,4-tetrahydroquinoline, 181.1 g (1 mole) of 6-bromohexanol, and 138.2 g (1 mole) of potassium carbonate in toluene is heated at 80° C. for 3 hours. The solution is cooled to room temperature, and the solids are removed by filtration. The solvent is removed in vacuo, and the N-hydroxyhexyltetrahydroquinoline is purified by chromatography (silica gel, hexane:ethyl acetate).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05247042 |
| 출처 데이터셋 | uspto-grants-1993_09 |
| ORD ID | ord-002d9f5f7d094a87a267a18d90638473 |
| 출처 메모 | uspto-grants-1993_09 |