Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 2-Benzo[b]furan-3-ylethylamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Benzofuran-3-acetonitrile | HCID 2769401 | — |
| 반응물 | Aluminium lithium hydride | HCID 21226445 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | 2-Benzo[b]furan-3-ylethylamine | HCID 12420812 | 79.4% |
반응 단계
A solution of 3.97 g (0.025 mole) of 3-cyanomethylbenzo[b]furan in 200 mL of diethyl ether was slowly added to a refluxing suspension of 3.84 g (0.1 mole) of lithium aluminum hydride in 400 mL of ether. The reaction was heated 3 hours., cooled and water was slowly added. The suspension was filtered through a pad of filter aid and the filtrate was evaporated to give 3.2 g of oily product. The hydrochloride salt has m.p. 183°-185° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04824849 |
| 출처 데이터셋 | uspto-grants-1989_04 |
| ORD ID | ord-2118182ae9544f038ba02bbca9f31c8c |
| 출처 메모 | uspto-grants-1989_04 |