Methanol → Methyl 4-phenylthiobenzoate

HRID 621636

반응식

HRID 621636 반응식
[C:1]1([C:7]2[CH:15]=[CH:14][C:10]([C:11]([OH:13])=[S:12])=[CH:9][CH:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.S(=O)(=O)(O)O.[CH3:21]O>>[C:1]1([C:7]2[CH:8]=[CH:9][C:10]([C:11]([O:13][CH3:21])=[S:12])=[CH:14][CH:15]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

참가 물질

4

반응물 3

HCID 887MethanolHCID 1118Sulfuric AcidHCID 178526127HCID 178526127, 화합물

생성물 1

HCID 54459547Methyl 4-phenylthiobenzoate

실험 절차

A mixture of 4-phenylthiobenzoic acid (26.29 g), conc. sulfuric acid (5 ml) and methanol (400 ml) is refluxed with stirring for 10 hours. After the reaction is completed, the reaction mixture is concentrated under reduced pressure, and to the residue is added ethyl acetate (400 ml). The mixture is washed with saturated aqueous sodium chloride solution (200 ml×3), dried over anhydrous magnesium sulfate, and concentrated under reduced pressure to give methyl 4-phenylthiobenzoate (27.44 g).

후처리

  1. temperatureis refluxed
  2. concentrationthe reaction mixture is concentrated under reduced pressure
  3. additionto the residue is added ethyl acetate (400 ml)
  4. washThe mixture is washed with saturated aqueous sodium chloride solution (200 ml×3)
  5. dry with materialdried over anhydrous magnesium sulfate
  6. concentrationconcentrated under reduced pressure

출처 및 근거

ORD 기록
ord-575a839db3484b71b69b3f4bec7ae1ed
출처 데이터셋
uspto-grants-1989_04
특허 번호
US04824834

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