Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 2-Acetyl-4-methoxycyclohexanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Ethyl Acetate | HCID 8857 | — |
| 반응물 | Sodium hydride | HCID 24758 | — |
| 반응물 | 4-Methoxycyclohexanone | HCID 535028 | — |
| 용매 | Benzene | HCID 241 | — |
| 용매 | Methanol | HCID 887 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 2-Acetyl-4-methoxycyclohexanone | HCID 13632724 | — |
반응 단계
1.12 g of 60% sodium hydride was added to 2.5 g of ethyl acetate and 1.78 g of a benzene solution of 4-methoxycyclohexanone was added thereto. After reacting at 40° C. for three hours, methanol was added to thereby decompose excessive sodium hydride and the reaction mixture was poured into water, neutralized with hydrochloric acid and extracted with ether to give 1.02 g of 2-acetyl4-methoxycyclohexanone. NMRδTMSCCl4 : 2.06 (3H, s). 1.7-2.5 (8H, s), 3.28 (3H , s), 3.4 (1H, m) and 15.9 (1H, s).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04824952 |
| 출처 데이터셋 | uspto-grants-1989_04 |
| ORD ID | ord-4cb7820e2c0d4756ac91ec0260e9fb9c |
| 출처 메모 | uspto-grants-1989_04 |