Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,3-Cyclohexanedione → Benzonitrile, 2-((3-oxo-1-cyclohexen-1-yl)amino)-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,3-Cyclohexanedione | HCID 10434 | — |
| 반응물 | 2-Aminobenzonitrile | HCID 72913 | — |
| 촉매 | p-Toluenesulfonic acid monohydrate | HCID 521998 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | Benzonitrile, 2-((3-oxo-1-cyclohexen-1-yl)amino)- | HCID 184360 | 93% |
반응 단계
A mixture of 2-aminobenzonitrile (120 g) and 1,3-cyclohexandione (120 g) in water (400 ml) was heated to 40° and 4-methylbenzenesulfonic acid monohydrate (6.2 g) was added, with stirring. The mixture was stirred at 40° for 1 hr. The mixture was filtered, and the filter cake was washed with water to provide 200 g (93%) of 2-(3-oxocyclohexen-1-yl)aminobenzonitrile, mp 191.4°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05247091 |
| 출처 데이터셋 | uspto-grants-1993_09 |
| ORD ID | ord-695590d38ba04361a966067c6963981f |
| 출처 메모 | uspto-grants-1993_09 |