Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Iodine → 2-Amino-4-(4-methoxyphenyl)thiazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Iodine | HCID 807 | — |
| 반응물 | 4'-Methoxyacetophenone | HCID 7476 | — |
| 반응물 | Thiourea | HCID 2723790 | — |
| 생성물 | 2-Amino-4-(4-methoxyphenyl)thiazole | HCID 159644 | 91.7% |
반응 단계
33.5 g of thiourea are added to 30 g of 4-methoxyacetophenone, 56 g of iodine are added and the mixture is kept at 100° C. for 5 hours. The reaction mixture is discharged onto water, powdered, washed several times with ether then with ammonia solution and finally with water, and dried. 37.8 g of 4-(4-methoxyphenyl)-thiazol-2-yl-amine of melting point 194°-205° C. are obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04769062 |
| 출처 데이터셋 | uspto-grants-1988_09 |
| ORD ID | ord-09dba717f1474456a3f92a8f3ab1376d |
| 출처 메모 | uspto-grants-1988_09 |