Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 6-Bromo-2-[2-(diisopropylamino)ethyl]phthalazin-1(2H)-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Potassium Hydroxide | HCID 14797 | — |
| 반응물 | 2-Chloroethyldiisopropylammonium chloride | HCID 77942 | — |
| 반응물 | 6-Bromophthalazin-1(2h)-one | HCID 11535918 | — |
| 용매 | Dimethyl Sulfoxide | HCID 679 | — |
| 생성물 | 6-Bromo-2-[2-(diisopropylamino)ethyl]phthalazin-1(2H)-one | HCID 21293334 | — |
반응 단계
6-Bromophthalazinone (11.2 gm, 0.05 mole) was slurried in 80 ml dimethylsulfoxide. To this was added 22 ml 45% KOH (0.25 mole). After stirring 10 minutes 16 gm 2-(diisopropylamino)ethyl chloride hydrochloride was added and the mixture stirred for 18 hours. A water bath was used to moderate the slightly exothermic reaction (temperature <=25°). Water (100 ml) was added to the reaction mixture, which was then stirred another hour.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04769369 |
| 출처 데이터셋 | uspto-grants-1988_09 |
| ORD ID | ord-8beea11fd514416690c0bd6c6de67784 |
| 출처 메모 | uspto-grants-1988_09 |