Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 62219생성일: 2026년 10월 25일
2-Propanone, methylhydrazone → 3-((1-Methyl-2-(propan-2-ylidene)hydrazinyl)methylene)pentane-2,4-dione
https://huagongshe.com/reaction/62219
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 2-Propanone, methylhydrazone | HCID 79840 | — |
| 반응물 | 3-(Ethoxymethylene)pentane-2,4-dione | HCID 240418 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | 3-((1-Methyl-2-(propan-2-ylidene)hydrazinyl)methylene)pentane-2,4-dione | HCID 23635272 | — |
반응 단계
3-(ethoxymethylene)pentane-2,4-dione (Preparation 2, 8.6 g) was dissolved in Ether (30 mL) and cooled to 0° C. The reaction solution was then slowly treated with 1-methyl-2-(propan-2-ylidene)hydrazine (Preparation 1, 4.8 g) dropwise over 5 minutes, and then warmed and stirred at room temperature overnight. The reaction solution was purified directly by flash column chromatography (Biotage Quad 25; Eluent: 20% EtOH in EtOAc) to afford the title compound as a light red solid. (9.1 g, 84.0%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 특허 번호 | US09446046B2 |
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| 출처 데이터셋 | uspto-grants-2016_09 |
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| ORD ID | ord-9d8001702bc04b4d93640fec5a09ac87 |
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| 출처 메모 | uspto-grants-2016_09 |
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