Ethyl isocyanoacetate → Ethyl4,5-dihydro-4-methyl-5-oxo-6-bromo-imidazo(1,5-a)quinazoline-3-carboxylate

반응식

[CH3:1][N:2]1[C:11](=[O:12])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][C:9]=2[Br:13])[NH:4][C:3]1=O.[N+:15]([CH2:17][C:18]([O:20][CH2:21][CH3:22])=[O:19])#[C-:16]>>[CH2:21]([O:20][C:18]([C:17]1[N:15]=[CH:16][N:4]2[C:5]3[C:10](=[C:9]([Br:13])[CH:8]=[CH:7][CH:6]=3)[C:11](=[O:12])[N:2]([CH3:1])[C:3]=12)=[O:19])[CH3:22]

참가 물질

반응물 2

HCID 533707Ethyl isocyanoacetate

HCID 14460512HCID 14460512, 화합물

생성물 1

HCID 21287685Ethyl4,5-dihydro-4-methyl-5-oxo-6-bromo-imidazo(1,5-a)quinazoline-3-carboxylate

실험 절차

M.p. 272° C. by reaction between 3-methyl-5-bromo-1,2,3,4-tetrahydro-2,4-dioxo-quinazoline and ethyl isocyanoacetate.

출처 및 근거

ORD 기록: ord-950b5de45ef445d89e5b01734248632e
출처 데이터셋: uspto-grants-1988_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04771051

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