Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-Methylmethanesulfonamide → 1-(4-fluoro-2-methylaminophenyl)-2-(N-methylsulphamoyl)ethanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-Methylmethanesulfonamide | HCID 97632 | — |
| 반응물 | Methyl 4-fluoro-2-(methylamino)benzoate | HCID 13474393 | — |
| 반응물 | Butyllithium | HCID 178418339 | — |
| 생성물 | 1-(4-fluoro-2-methylaminophenyl)-2-(N-methylsulphamoyl)ethanone | HCID 21291484 | — |
반응 단계
In a similar manner to that described in Example 12(a), N-methylmethanesulphonamide was reacted with n-butyl lithium and the product reacted with methyl 4-fluoro-2-methylaminobenzoate to give the novel compound 1-(4-fluoro-2-methylaminophenyl)-2-(N-methylsulphamoyl)ethanone, m.p. 140°-142°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04772614 |
| 출처 데이터셋 | uspto-grants-1988_09 |
| ORD ID | ord-63e621efc46e492b838d0e66c85af94a |
| 출처 메모 | uspto-grants-1988_09 |