2-Thiophenecarbonyl chloride → Anthrimide

HRID 622839

반응식

HRID 622839 반응식
[CH:1]1[CH:6]=[C:5]2[C:7]([C:9]3[C:14]([C:15](=[O:16])[C:4]2=[CH:3][CH:2]=1)=[C:13]([NH:17][C:18]1[CH:23]=[CH:22][C:21](N)=[C:20]2[C:25]([C:27]4[C:32]([C:33](=[O:34])[C:19]=12)=[CH:31][CH:30]=[CH:29][CH:28]=4)=[O:26])[CH:12]=[CH:11][C:10]=3N)=[O:8].S1C=CC=C1C(Cl)=O>[N+](C1C=CC=CC=1)([O-])=O>[CH:1]1[CH:6]=[C:5]2[C:7]([C:9]3[CH:10]=[CH:11][CH:12]=[C:13]([NH:17][C:18]4[C:19]5[C:33]([C:32]6[C:27]([C:25](=[O:26])[C:20]=5[CH:21]=[CH:22][CH:23]=4)=[CH:28][CH:29]=[CH:30][CH:31]=6)=[O:34])[C:14]=3[C:15](=[O:16])[C:4]2=[CH:3][CH:2]=1)=[O:8]

참가 물질

4

반응물 2

HCID 789282-Thiophenecarbonyl chlorideHCID 178507708HCID 178507708, 화합물

생성물 1

HCID 6700Anthrimide수율 145.4%

시약·촉매·용매 1

HCID 7416Nitrobenzene용매

실험 절차

9.2 g of 4,4'-diamino-1,1'-dianthrimide are heated in 75 ml of nitrobenzene to 145°-150° C. 6.5 g of thiophene-2-carboxylic acid chloride are then added dropwise over a period of 30 minutes. The temperature of the suspension is increased to 170°-175° C. over a period of 2 hours and the suspension is stirred for 2 hours at that temperature. After cooling, the product is filtered off and washed with nitrobenzene and ethanol. 12.5 g of the anthrimide of the formula (2) are obtained. The anthrimide is converted into the carbazole compound of the formula (1) in accordance with Example 1, paragraph 2.

후처리

  1. temperatureThe temperature of the suspension is increased to 170°-175° C. over a period of 2 hours
  2. temperatureAfter cooling
  3. filtrationthe product is filtered off
  4. washwashed with nitrobenzene and ethanol

출처 및 근거

ORD 기록
ord-d0f4e1a4b9214e4f98160dd267039cb7
출처 데이터셋
uspto-grants-1988_09
특허 번호
US04772725

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