3-Bromo-5-(1-hydroxypropyl)isoxazole → 1-(3-Bromo-1,2-oxazol-5-yl)ethan-1-one

반응식

COC1C=C(C(O)C)ON=1.[Br:11][C:12]1[CH:16]=[C:15]([CH:17]([OH:20])[CH2:18]C)[O:14][N:13]=1.BrC1C=C(C(O)CCC)ON=1>>[Br:11][C:12]1[CH:16]=[C:15]([C:17](=[O:20])[CH3:18])[O:14][N:13]=1

참가 물질

반응물 3

HCID 138020893-Bromo-5-(1-hydroxypropyl)isoxazole

HCID 138020903-Bromo-5-(1-hydroxybutyl)-isoxazole

HCID 212922791-(3-Methoxyisoxazol-5-YL)ethan-1-OL

생성물 1

HCID 136269711-(3-Bromo-1,2-oxazol-5-yl)ethan-1-one

실험 절차

In a similar manner 3-methoxy-5-(1-hydroxyethyl)-isoxazole, 3-bromo-5-(1-hydroxypropyl)-isoxazole and 3-bromo-5-(1-hydroxybutyl)-isoxazole were oxidized to afford

후처리

customto afford

출처 및 근거

ORD 기록: ord-037ecdf04a4d436b8e1f063d314741d7
출처 데이터셋: uspto-grants-1988_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04772719

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