Oxalyl chloride → 1-Methyl-1,4-dihydro-2,3-quinoxalinedione
반응식
[C:1](Cl)(=[O:5])[C:2](Cl)=[O:3].[CH3:7][NH:8][C:9]1[CH:15]=[CH:14][CH:13]=[CH:12][C:10]=1[NH2:11]>C(N(CC)CC)C.C1(C)C=CC=CC=1>[CH3:7][N:8]1[C:9]2[C:10](=[CH:12][CH:13]=[CH:14][CH:15]=2)[NH:11][C:2](=[O:3])[C:1]1=[O:5]참가 물질
5
실험 절차
A mixture of 12 g of 98% oxalylchloride in 19.5 ml of triethylamine and 50 ml of toluene was added dropwise to a stirred solution of 8.5 g of o-N-methylamino aniline in 80 ml of toluene. The resulting mixture was heated at reflux for one hour. The precipitate was washed with ether. The residue was stirred with water and filtered to give 1,2,3,4-tetrahydro-1-methyl-2,3-dioxo-quinoxaline.
후처리
- temperatureThe resulting mixture was heated
- temperatureat reflux for one hour
- washThe precipitate was washed with ether
- filtrationfiltered
출처 및 근거
- ORD 기록
- ord-b0fa077b0ee740b99315c72b14218da4
- 출처 데이터셋
- uspto-grants-1988_09
- 특허 번호
- US04774245
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