Oxalyl chloride → 1-Methyl-1,4-dihydro-2,3-quinoxalinedione

HRID 623183

반응식

HRID 623183 반응식
[C:1](Cl)(=[O:5])[C:2](Cl)=[O:3].[CH3:7][NH:8][C:9]1[CH:15]=[CH:14][CH:13]=[CH:12][C:10]=1[NH2:11]>C(N(CC)CC)C.C1(C)C=CC=CC=1>[CH3:7][N:8]1[C:9]2[C:10](=[CH:12][CH:13]=[CH:14][CH:15]=2)[NH:11][C:2](=[O:3])[C:1]1=[O:5]

참가 물질

5

반응물 2

HCID 65578Oxalyl chlorideHCID 78498N-Methyl-o-phenylenediamine

생성물 1

HCID 6006271-Methyl-1,4-dihydro-2,3-quinoxalinedione

시약·촉매·용매 2

HCID 1140Toluene용매2회HCID 8471Triethylamine용매

실험 절차

A mixture of 12 g of 98% oxalylchloride in 19.5 ml of triethylamine and 50 ml of toluene was added dropwise to a stirred solution of 8.5 g of o-N-methylamino aniline in 80 ml of toluene. The resulting mixture was heated at reflux for one hour. The precipitate was washed with ether. The residue was stirred with water and filtered to give 1,2,3,4-tetrahydro-1-methyl-2,3-dioxo-quinoxaline.

후처리

  1. temperatureThe resulting mixture was heated
  2. temperatureat reflux for one hour
  3. washThe precipitate was washed with ether
  4. filtrationfiltered

출처 및 근거

ORD 기록
ord-b0fa077b0ee740b99315c72b14218da4
출처 데이터셋
uspto-grants-1988_09
특허 번호
US04774245

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