2',4'-Difluoro-biphenyl-4-sulfonyl chloride → HCID 178501245, 화합물

HRID 623382노트

반응식

HRID 623382 반응식
[F:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[C:9]1[CH:14]=[CH:13][C:12]([S:15](Cl)(=[O:17])=[O:16])=[CH:11][CH:10]=1.[NH2:19][C@H:20]1[CH2:25][CH2:24][C@H:23]([C:26]([O:28][CH3:29])=[O:27])[CH2:22][CH2:21]1>>[F:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[C:9]1[CH:14]=[CH:13][C:12]([S:15]([NH:19][C@H:20]2[CH2:21][CH2:22][C@H:23]([C:26]([O:28][CH3:29])=[O:27])[CH2:24][CH2:25]2)(=[O:17])=[O:16])=[CH:11][CH:10]=1

참가 물질

3

반응물 2

HCID 448910942',4'-Difluoro-biphenyl-4-sulfonyl chlorideHCID 178501207HCID 178501207, 화합물

생성물 1

HCID 178501245HCID 178501245, 화합물

실험 절차

Using a method analogous to Method A with 2′,4′-difluorobiphenyl-4-sulfonyl chloride and methyl trans-4-aminocyclohexanecarboxylate, the title compound was obtained as a white solid.

출처 및 근거

ORD 기록
ord-c37ad968adb54e5184cc8eb625203d11
출처 데이터셋
uspto-grants-2016_04
특허 번호
US09302984B2

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