tert-Butylsulfinamide, (R)-(+)- → HCID 87426647, 화합물

HRID 623546노트

반응식

HRID 623546 반응식
[F:1][C:2]([F:16])([O:6][C:7]1[CH:8]=[C:9]([C:13](=O)[CH3:14])[CH:10]=[CH:11][CH:12]=1)[CH:3]([F:5])[F:4].[CH3:17][C:18]([S@:21]([NH2:23])=[O:22])([CH3:20])[CH3:19]>>[CH3:17][C:18]([S@:21]([NH:23][CH:13]([C:9]1[CH:10]=[CH:11][CH:12]=[C:7]([O:6][C:2]([F:16])([F:1])[CH:3]([F:5])[F:4])[CH:8]=1)[CH3:14])=[O:22])([CH3:20])[CH3:19]

참가 물질

3

반응물 2

HCID 10964479tert-Butylsulfinamide, (R)-(+)-HCID 716505571-[3-(1,1,2,2-Tetrafluoroethoxy)phenyl]ethanone

생성물 1

HCID 87426647HCID 87426647, 화합물수율 81%

실험 절차

The title compound is prepared in 81% yield (0.92 g, colorless oil) from 1-(3-(1,1,2,2-tetrafluoroethoxy)phenyl)ethanone (0.79 g, 3.36 mmol, Step-2) and (R)-2-methylpropane-2-sulfinamide by the similar manner in Step-4 of Amine-1.

출처 및 근거

ORD 기록
ord-7164bc71ce80479ba965299431e79cad
출처 데이터셋
uspto-grants-2016_04
특허 번호
US09302991B2

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