Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Aminopicolinic acid → 3-amino-N-(1-(6-(2,2,2-trifluoroethoxy)pyridin-3-yl)ethyl)picolinamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Aminopicolinic acid | HCID 73836 | — |
| 반응물 | 1-[6-(2,2,2-Trifluoroethoxy)-pyridin-3-yl]-ethylamine hydrochloride | HCID 67509413 | — |
| 생성물 | 3-amino-N-(1-(6-(2,2,2-trifluoroethoxy)pyridin-3-yl)ethyl)picolinamide | HCID 67509770 | 74% |
반응 단계
The title compound is prepared in 74% yield (98 mg, a white solid) from (−)-1-(6-(2,2,2-trifluoroethoxy)pyridin-3-yl)ethanamine hydrochloride (100 mg, 0.39 mmol, Amine-1, single enantiomer) and 3-aminopicolinic acid (54 mg, 0.39 mmol) by the similar manner in Step-1 of Example-8.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09302991B2 |
| 출처 데이터셋 | uspto-grants-2016_04 |
| ORD ID | ord-1e2105a334bf4dafb9c06265ff6af43e |
| 출처 메모 | uspto-grants-2016_04 |