Acetyl chloride → HCID 67510224, 화합물

HRID 623619노트

반응식

HRID 623619 반응식
[NH2:1][C:2]1[N:7]=[C:6]([C:8]([NH:10][CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[C:14]([O:18][C:19]([F:22])([F:21])[F:20])[CH:13]=2)=[O:9])[CH:5]=[CH:4][N:3]=1.[C:23](Cl)(=[O:25])[CH3:24]>>[C:23]([NH:1][C:2]1[N:7]=[C:6]([C:8]([NH:10][CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[C:14]([O:18][C:19]([F:22])([F:20])[F:21])[CH:13]=2)=[O:9])[CH:5]=[CH:4][N:3]=1)(=[O:25])[CH3:24]

참가 물질

3

반응물 2

HCID 6367Acetyl chlorideHCID 675097342-amino-N-(3-(trifluoromethoxy)benzyl)pyrimidine-4-carboxamide

생성물 1

HCID 67510224HCID 67510224, 화합물

실험 절차

The title compound is prepared from 2-amino-N-(3-(trifluoromethoxy)benzyl)pyrimidine-4-carboxamide (15 mg, 0.05 mmol, Step-1) and acetyl chloride (11 mg, 0.14 mmol) according to the procedure similar to that described in Step-2 of Example 8.

출처 및 근거

ORD 기록
ord-9f8fe324af0649d2bcd9733b7d5e6620
출처 데이터셋
uspto-grants-2016_04
특허 번호
US09302991B2

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