Oxonium, trimethyl-, tetrafluoroborate(1-) (1:1) → 1-Methoxy-4-methyl-2-[4-(trifluoromethyl)phenyl]-2H-1,2,3-triazolium tetrafluoroborate

HRID 623688

반응식

HRID 623688 반응식
[CH3:1][C:2]1[CH:6]=[N+:5]([O-:7])[N:4]([C:8]2[CH:13]=[CH:12][C:11]([C:14]([F:17])([F:16])[F:15])=[CH:10][CH:9]=2)[N:3]=1.[F:18][B-:19]([F:22])([F:21])[F:20].[CH3:23][O+](C)C>ClCCl>[F:18][B-:19]([F:22])([F:21])[F:20].[CH3:23][O:7][N+:5]1[N:4]([C:8]2[CH:9]=[CH:10][C:11]([C:14]([F:15])([F:17])[F:16])=[CH:12][CH:13]=2)[N:3]=[C:2]([CH3:1])[CH:6]=1

참가 물질

4

반응물 2

HCID 2735153Oxonium, trimethyl-, tetrafluoroborate(1-) (1:1)HCID 901094824-Methyl-2-[4-(trifluoromethyl)phenyl]-2H-1,2,3-triazole 1-oxide2회

생성물 1

HCID 901113321-Methoxy-4-methyl-2-[4-(trifluoromethyl)phenyl]-2H-1,2,3-triazolium tetrafluoroborate

시약·촉매·용매 1

HCID 6344Dichloromethane용매

반응 조건

온도
23 °C

실험 절차

To a stirred solution of 4-methyl-2-[4-(trifluoromethyl)phenyl]-2H-1,2,3-triazole 1-oxide (i.e. the product of Step A, 5.22 g, 21.5 mmol) in dichloromethane (100 mL) was added trimethyloxonium tetrafluoroborate (4.13 g, 27.9 mmol). The reaction mixture was stirred at 23° C. for 65 h, then concentrated under reduced pressure to afford a crude mixture of the title compound as a brown oil which was used directly in the next step without further purification.

후처리

  1. concentrationconcentrated under reduced pressure
  2. customto afford a crude

출처 및 근거

ORD 기록
ord-0dd6ad38af624003b9fb69ef32ddf35a
출처 데이터셋
uspto-grants-2016_04
특허 번호
US09302999B2

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