5-m-Tolyl-thiazole-4-carboxylic acid → N-(1-(2-Aminoethyl)-1H-pyrazol-4-yl)-5-(m-tolyl)thiazole-4-carboxamide
반응식
[NH2:1][CH2:2][CH2:3][N:4]1[CH:8]=[C:7]([NH:9][C:10]([C:12]2[N:13]=[CH:14]O[C:16]=2[C:17]2[CH:18]=[C:19]([CH3:23])[CH:20]=[CH:21][CH:22]=2)=[O:11])[CH:6]=[N:5]1.C1(C)C=CC=C(C2[S:34]C=NC=2C(O)=O)C=1>>[NH2:1][CH2:2][CH2:3][N:4]1[CH:8]=[C:7]([NH:9][C:10]([C:12]2[N:13]=[CH:14][S:34][C:16]=2[C:17]2[CH:18]=[C:19]([CH3:23])[CH:20]=[CH:21][CH:22]=2)=[O:11])[CH:6]=[N:5]1참가 물질
3
실험 절차
The title compound was synthesized according to above mentioned procedure for N-(1-(2-aminoethyl)-1H-pyrazol-4-yl)-5-(m-tolyl)oxazole-4-carboxamide, starting from 5-(m-tolyl)thiazole-4-carboxylic acid. LC-MS conditions B: tR=0.54 min, [M+H]+=328.10.
출처 및 근거
- ORD 기록
- ord-8efcdce053454b5690b5e93267db9295
- 출처 데이터셋
- uspto-grants-2016_04