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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 625247생성일: 2026년 10월 25일

N-Benzyl-2-morpholinoethanamine → N1-benzyl-N1-(2-morpholinoethyl)-N3-(4-(piperidin-1-yl)-2-(4-((3-(trifluoromethyl)benzyl)carbamoyl)pyridin-2-yl)phenyl)isophthalamide

https://huagongshe.com/reaction/625247

반응식

참여 물질

역할이름HCID투입량
반응물N-Benzyl-2-morpholinoethanamineHCID 4719951—
반응물3-((2-(4-((3-(Trifluoromethyl)benzyl)carbamoyl)pyridin-2-yl)-4-(piperidin-1-yl)phenyl)carbamoyl)benzoic acidHCID 66586784—
반응물N1-methyl-N1-(2-morpholinoethyl)-N3-(4-(piperidin-1-yl)-2-(4-((3-(trifluoromethyl)benzyl)carbamoyl)pyridin-2-yl)phenyl)isophthalamideHCID 69631879—
생성물N1-benzyl-N1-(2-morpholinoethyl)-N3-(4-(piperidin-1-yl)-2-(4-((3-(trifluoromethyl)benzyl)carbamoyl)pyridin-2-yl)phenyl)isophthalamideHCID 68097155—

반응 단계

This compound was prepared from 3-((2-(4-((3-(trifluoromethyl)benzyl)carbamoyl)pyridin-2-yl)-4-(piperidin-1-yl)phenyl)carbamoyl)benzoic acid 4.1e using the procedure described for the preparation of N1-methyl-N1-(2-morpholinoethyl)-N3-(4-(piperidin-1-yl)-2-(4-((3-(trifluoromethyl)benzyl)carbamoyl)pyridin-2-yl)phenyl)isophthalamide 4.8. N-benzyl-2-morpholinoethanamine was used as the amine component in this coupling. MS (ES, m/z): 805 [M+H]+

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09301951B2
출처 데이터셋uspto-grants-2016_04
ORD IDord-e409128282b14647938432ea28cc5745
출처 메모uspto-grants-2016_04