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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 625254생성일: 2026년 10월 26일

Methyl(2-(morpholin-4-yl)ethyl)amine → N1-methyl-N1-(2-morpholinoethyl)-N3-(4-(piperidin-1-yl)-2-(4-((3-(trifluoromethyl)benzyl)carbamoyl)pyridin-2-yl)phenyl)isophthalamide

https://huagongshe.com/reaction/625254

반응식

참여 물질

역할이름HCID투입량
반응물Methyl(2-(morpholin-4-yl)ethyl)amineHCID 14979282—
반응물3-((2-(4-((3-(Trifluoromethyl)benzyl)carbamoyl)pyridin-2-yl)-4-(piperidin-1-yl)phenyl)carbamoyl)benzoic acidHCID 66586784—
반응물N1-Ethyl-N1-(2-morpholinoethyl)-N3-(4-(piperidin-1-yl)-2-(4-((3-(trifluoromethyl)benzyl)carbamoyl)pyridin-2-yl)phenyl)isophthalamideHCID 69631832—
생성물N1-methyl-N1-(2-morpholinoethyl)-N3-(4-(piperidin-1-yl)-2-(4-((3-(trifluoromethyl)benzyl)carbamoyl)pyridin-2-yl)phenyl)isophthalamideHCID 69631879—

반응 단계

This compound was prepared by coupling N-methyl-2-morpholinoethylamine to 3-((4-(piperidin-1-yl)-2-(4-((3-(trifluoromethyl)benzyl)carbamoyl)pyridin-2-yl)phenyl)-carbamoyl)benzoic acid 4.1e, using the procedure described for the preparation of N1-ethyl-N1-(2-morpholinoethyl)-N3-(4-(piperidin-1-yl)-2-(4-((3-(trifluoromethyl)benzyl)-carbamoyl)pyridin-2-yl)phenyl)isophthalamide 4.8. MS (ES, m/z): 743 [M+H]+

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09301951B2
출처 데이터셋uspto-grants-2016_04
ORD IDord-7a3a0aa7a25e4b8e9612b5a7e056fcf8
출처 메모uspto-grants-2016_04