Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 625988생성일: 2026년 10월 26일
Potassium Hydroxide → 2-Fluoro-6-(4-{2-[(6-fluoropyridin-2-yl)oxy]ethyl}-2-methoxyphenoxy)pyridine
https://huagongshe.com/reaction/625988
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Potassium Hydroxide | HCID 14797 | — |
| 반응물 | Homovanillyl alcohol | HCID 16928 | — |
| 반응물 | 2,6-Difluoropyridine | HCID 73934 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 2-Fluoro-6-(4-{2-[(6-fluoropyridin-2-yl)oxy]ethyl}-2-methoxyphenoxy)pyridine | HCID 24785926 | — |
반응 단계
To a suspension of KOH (2 mmol; 112 mg) in anhydrous DMF (1 mL) under argon, was added 4-(2-hydroxyethyl)-2-methoxyphenol (1 mmol; 168 mg) followed by 2,6-Difluoropyridine (1 mmol; 0.1 ml). The reaction mixture was stirred at 110° C. for 20 h.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US09309179B2 |
|---|
| 출처 데이터셋 | uspto-grants-2016_04 |
|---|
| ORD ID | ord-c5873df0ab9942df83120de2cb1d9f1b |
|---|
| 출처 메모 | uspto-grants-2016_04 |
|---|
