Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-(3,4-Difluorophenyl)ethan-1-one → 1-{4-[2-(Benzyloxy)-4-ethylphenoxy]-3-fluorophenyl}ethanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-(3,4-Difluorophenyl)ethan-1-one | HCID 123052 | — |
| 반응물 | 3-Fluoro-2-nitropyridine | HCID 2762802 | — |
| 반응물 | 2-(Benzyloxy)-4-ethylphenol | HCID 59191243 | — |
| 생성물 | 1-{4-[2-(Benzyloxy)-4-ethylphenoxy]-3-fluorophenyl}ethanone | HCID 59191401 | 96% |
반응 단계
According to the procedure of example 21 (a3) except substituting 4-Ethyl-2-methoxy phenol by 2-(benzyloxy)-4-ethylphenol (1.3 g, 5.7 mmol) and 3-Fluoro-2-nitropyridine by 1-(3,4-difluorophenyl)ethanone (0.98 g, 6.27 mmol), the title compound was prepared as a clear oil in 96% yield (2 g) and used without further purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09309179B2 |
| 출처 데이터셋 | uspto-grants-2016_04 |
| ORD ID | ord-5af2dfcfa98c421bb2f57be5933723f6 |
| 출처 메모 | uspto-grants-2016_04 |