6-Chloronicotinoyl Chloride → 6-Chloro-N-methoxy-N-methylnicotinamide

HRID 627493노트

반응식

HRID 627493 반응식
[Cl:1][C:2]1[N:7]=[CH:6][C:5]([C:8](Cl)=[O:9])=[CH:4][CH:3]=1.ClC1C=CC(C(C2N(C)C=NC=2)=O)=CN=1.FC1N=CC(C(Cl)=O)=CC=1.FC1N=CC([C:43]([N:45]([O:47][CH3:48])C)=O)=CC=1>>[Cl:1][C:2]1[N:7]=[CH:6][C:5]([C:8]([N:45]([O:47][CH3:48])[CH3:43])=[O:9])=[CH:4][CH:3]=1

참가 물질

5

반응물 4

HCID 27821656-Chloronicotinoyl ChlorideHCID 120166732-Chloro-5-[(1-methyl-1H-imidazol-5-yl)carbonyl]pyridineHCID 146236022-Fluoropyridine-5-carbonyl chlorideHCID 587671286-Fluoro-N-methoxy-N-methylpyridine-3-carboxamide

생성물 1

HCID 114355976-Chloro-N-methoxy-N-methylnicotinamide

실험 절차

The title compound was prepared using 6-chloropyridine-3-carbonyl chloride (Intermediate 22, step a) in place of 6-fluoropyridine-3-carbonyl chloride according to the procedure described for Intermediate 21, step b.

출처 및 근거

ORD 기록
ord-523d37c3c2234f9c8e902158e9a2624a
출처 데이터셋
uspto-grants-2016_04
특허 번호
US09309222B2

반응 노트

불러오는 중…