Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Morpholine → 7-Hydroxyisoflavone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Morpholine | HCID 8083 | — |
| 반응물 | Ethylorthoformate | HCID 53630039 | — |
| 반응물 | 2,4-Dihydroxy-phenyl-benzyl-ketone | HCID 54014987 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | 7-Hydroxyisoflavone | HCID 5376891 | 90.6% |
반응 단계
A mixture of 20 g (0.0877 mole) 2,4-dihydroxy-phenyl-benzyl-ketone, 20.7 g (0.14 mole) ethyl-orthoformate and 1 ml of morpholine is stirred on a hot water bath. Crystallization starts after heating for 25 minutes. The inert temperature falls back to 87° C. from 96° C. during the reaction. After stirring for 5 hours the reaction mixture is diluted with 48 ml of chloroform and then one may proceed as disclosed in Example 5. 18.9 g of 7-hydroxy-isoflavone are obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05247102 |
| 출처 데이터셋 | uspto-grants-1993_09 |
| ORD ID | ord-90f5082eeee942519d56cfae78d6b65a |
| 출처 메모 | uspto-grants-1993_09 |