Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-(4-Hydroxyphenyl)propionic acid → Benzenepropanoic acid, 4-hydroxy-, methyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-(4-Hydroxyphenyl)propionic acid | HCID 10394 | — |
| 반응물 | 1,4-Dioxane hydrochloride | HCID 20443148 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | Benzenepropanoic acid, 4-hydroxy-, methyl ester | HCID 79706 | 100.5% |
반응 단계
After 3-(4-hydroxy-phenyl)propionic acid (3 g, 18 mmol) was added with MeOH (6 mL), 4M HCl/dioxane solution (18 mL, 72 mmol) was added thereto, and the mixture was stirred at room temperature for 3 hours. The reactant was concentrated, added with EtOAc, and then washed with NaCl aqueous solution. The organic layer was separated, dried with MgSO4, and filtered to obtain the title compound (3.26 g, 99%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09447044B2 |
| 출처 데이터셋 | uspto-grants-2016_09 |
| ORD ID | ord-ec3f833bd73143d4a3ef43c7709226b4 |
| 출처 메모 | uspto-grants-2016_09 |