(4-Methoxy-2,5-dimethylphenyl)boronic acid → 1-(2,5-dimethyl-4-methoxy-phenyl)-3-methyl-1H-pyrazole

HRID 628520노트

반응식

HRID 628520 반응식
[CH3:1][C:2]1[CH:7]=[C:6]([O:8][CH3:9])[C:5]([CH3:10])=[CH:4][C:3]=1B(O)O.[CH3:14][C:15]1[CH:19]=[CH:18][NH:17][N:16]=1>>[CH3:1][C:2]1[CH:7]=[C:6]([O:8][CH3:9])[C:5]([CH3:10])=[CH:4][C:3]=1[N:17]1[CH:18]=[CH:19][C:15]([CH3:14])=[N:16]1

참가 물질

3

반응물 2

HCID 5233015(4-Methoxy-2,5-dimethylphenyl)boronic acidHCID 178428694HCID 178428694, 화합물

생성물 1

HCID 1182363091-(2,5-dimethyl-4-methoxy-phenyl)-3-methyl-1H-pyrazole

실험 절차

A similar reaction to Reference Preparation example 33 using 2,5-dimethyl-4-methoxy-phenylboronic acid instead of 4-methoxy-3-methyl-phenylboronic acid, and using 3-methyl-1H-pyrazole instead of 3,4,5-trimethyl-1H-pyrazole gave 1-(2,5-dimethyl-4-methoxy-phenyl)-3-methyl-1H-pyrazole.

후처리

  1. customA similar reaction

출처 및 근거

ORD 기록
ord-ffd50c8f5d6b4c59841cd87e1aa05da9
출처 데이터셋
uspto-grants-2016_04
특허 번호
US09314023B2

반응 노트

불러오는 중…