Isopropyl iodide → 3-Isopropylsulfanyl-pyrazine-2-carboxylic acid methyl ester

HRID 62864노트

반응식

HRID 62864 반응식
[CH3:1][O:2][C:3]([C:5]1[C:10]([SH:11])=[N:9][CH:8]=[CH:7][N:6]=1)=[O:4].I[CH:13]([CH3:15])[CH3:14]>>[CH3:1][O:2][C:3]([C:5]1[C:10]([S:11][CH:13]([CH3:15])[CH3:14])=[N:9][CH:8]=[CH:7][N:6]=1)=[O:4]

참가 물질

3

반응물 2

HCID 6362Isopropyl iodideHCID 178499101HCID 178499101, 화합물

생성물 1

HCID 901180683-Isopropylsulfanyl-pyrazine-2-carboxylic acid methyl ester수율 61%

실험 절차

3-Mercapto-pyrazine-2-carboxylic acid methyl ester (0.35 g, 2.0 mmol) obtained in Step A and 2-iodopropane were reacted in the same manner as in Step A of Preparation Example 5 to obtain the title compound (0.267 g, 61%).

출처 및 근거

ORD 기록
ord-9c6637ca917049fabc1a23509cbfe685
출처 데이터셋
uspto-grants-2016_09
특허 번호
US09447044B2

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