Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Toluenesulfonyl chloride → 3-[4-(p-Toluenesulfonyloxy)butyl]-1H-indole-5-carbonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Toluenesulfonyl chloride | HCID 7397 | — |
| 반응물 | 3-(4-Hydroxybutyl)-1H-indole-5-carbonitrile | HCID 12150985 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 3-[4-(p-Toluenesulfonyloxy)butyl]-1H-indole-5-carbonitrile | HCID 56952267 | — |
반응 단계
3-[4-(p-Toluenesulfonyloxy)butyl]-1H-indole-5-carbonitrile was prepared by reacting 3-(4-hydroxybutyl)-1H-indole-5-carbonitrile with p-toluenesulfonyl chloride in the presence of base in dichloromethane as per the process exemplified in example 2 of Chinese Patent Application Publication No. CN 102267932 A.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09315456B2 |
| 출처 데이터셋 | uspto-grants-2016_04 |
| ORD ID | ord-de1fb67b6cc7491288925f091e7cefa9 |
| 출처 메모 | uspto-grants-2016_04 |