Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl 3-(4-hydroxyphenyl)-2-methylpropanoate → 3-[4-(2-Isopropylsulfanyl-pyridin-3-ylmethoxy)-phenyl]-2-methyl-propionic acid ethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl 3-(4-hydroxyphenyl)-2-methylpropanoate | HCID 20748401 | — |
| 반응물 | 3-Chloromethyl-2-isopropylsulfanyl-pyridine | HCID 53816681 | — |
| 생성물 | 3-[4-(2-Isopropylsulfanyl-pyridin-3-ylmethoxy)-phenyl]-2-methyl-propionic acid ethyl ester | HCID 90118201 | 53.5% |
반응 단계
3-Chloromethyl-2-isopropylsulfanyl-pyridine (0.063 g, 0.31 mmol) obtained in Step C of Preparation Example 1 and 3-(4-hydroxy-phenyl)-2-methyl-propionic acid ethyl ester (0.065 g, 0.31 mmol) obtained in Step B of Preparation Example 3 were reacted in the same manner as in Step A of Example 1 to obtain the title compound (0.062 g, 53%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09447044B2 |
| 출처 데이터셋 | uspto-grants-2016_09 |
| ORD ID | ord-5bf84665a5bb4ea2846f25921390c4cc |
| 출처 메모 | uspto-grants-2016_09 |